Professor Hildick-Smith specialises in Cardiac Interventions and is an internationally well-known expert. He is the immediate past-President of the British Cardiovascular Interventions Society and author of >500 peer-reviewed publications.

He is head of the Department of Cardiology and leads the Cardiac Research Unit in Brighton which has 40 studies ongoing at any one time. He has additional roles with NHS England and Specialist Commissioning.

His particular interests are in coronary interventions with drug-coated balloons and stents, and structural heart interventions (aortic valve implants, mitral valve implants, tricuspid valve implants, paravalvular leak closure, atrial septal defect closure, patent foramen ovale closure and left atrial appendage occlusion).